Thank you for joining us at the 2025 World Transplant Congress, Booth 814. This Information Hub includes WTC 2025 presentations, abstracts, and posters on Hypothermic Oxygenated Perfusion (HOPE).
Symposium
Hypothermic Oxygenated Perfusion (HOPE): From Science to Clinical Impact
Chairperson/Moderator: Garret Roll, MD, University of California San Francisco, San Francisco, CA
Agenda
Hypothermic Oxygenated Perfusion Clinical Evidence: Bridge to HOPE Trial
Speaker: David Foley, MD, University of Wisconsin School of Medicine and Public Health, Madison, WI
Viability Assessment in HOPE
Speaker: Prof. Andrea Schlegel, Cleveland Clinic Foundation, Cleveland, OH
Economic Impact of Hypothermic Oxygenated Liver Perfusion
Speaker: David Axelrod, MD, University Hospitals Cleveland Medical Center, OH
This program was approved by the WTC 2025 Scientific Committee as an independent activity held in conjunction with the World Transplant Congress 2025. This program is not sponsored or endorsed by WTC 2025.
Plenary Session
View Abstract | View Presentation
Plenary Session Title: Plenary Abstracts 2
Presentation Title: Hypothermic-Oxygenated and Normothermic Machine Perfusion: A Risk-Matched Post-Hoc Comparison of the Bridge to Hope Randomized Trial with Prospectively Collected Institutional Outcomes
Date/Time: Monday August 4, 2025, 10:30 AM – 10:45 AM PT
Location: Moscone Center, SFO Ballroom
Presenter: Chase J. Wehrle, MD, Cleveland Clinic, Cleveland, OH, Winner of the ILTS 2025 Young Investigators Award
Presentations, Abstracts, and Posters
All presentations, abstracts, and posters will be available after the conference.
View Abstract
Late-Breaking Oral Abstract:
Session Title: Liver Transplantation and Machine Perfusion
Presentation Title: Novel Approach to Viability Assessment of Split Liver Grafts Using Hypothermic Oxygenated Perfusion
Poster Number: LOA02.7
Date/Time: Sunday August 3, 2025, 3:11 PM – 3:20 PM PT
Location: Moscone Center, Room 9
Speaker: Geofia Crasta, MD, Department of Inflammation and Immunity, Lerner Research Institute – Cleveland Clinic, Cleveland, OH
View Abstract
Late-Breaking Oral Abstract:
Session Title: Liver Transplantation and Machine Perfusion
Presentation Title: Clinical and Logistical Impact of Machine Perfusion in a Low Volume Liver Transplant Center
Poster Number: LOA02.8
Date/Time: Sunday August 3, 2025, 3:20 PM – 3:29 PM PT
Location: Moscone Center, Room 9
Speaker: Marco Maria Pascale, MD, Policlinico Universitario Fondazione Agostino Gemelli, Rome, Italy
View Abstract | View Poster | View Presentation
Late-Breaking Oral Abstract:
Session Title: Liver Transplantation: New Techniques, Immunosuppression Strategies and Patient Outcomes
Presentation Title: Immunomodulation through Hypothermic Oxygenated Perfusion in Liver Transplantation: Biomarker Analysis in Peripheral Blood
Poster Number: LOA06.5
Date/Time: Tuesday August 5, 2025, 8:51 AM – 9:00 AM PT
Location: Moscone Center, Room 11
Speaker: Marco Maria Pascale, MD, Policlinico Universitario Fondazione Agostino Gemelli, Rome, Italy
View Abstract
Late-Breaking Oral Abstract:
Session Title: Past Meets Future: Redefining the Limits of Transplantation
Presentation Title: Hypothermic Oxygenated Perfusion (HOPE) in Pediatric Liver Transplantation: A Multicenter Study
Poster Number: LOA08.2
Date/Time: Wednesday August 6, 2025, 10:09 AM – 10:18 AM PT
Location: Moscone Center, Room 4
Speaker: Francisco Hernández Oliveros, MD, Hospital Universitario La Paz, Madrid, Spain
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Poster Presentation:
Session Title: Liver
Presentation Title: Impact of Hypothermic Oxygenated Machine Perfusion on Ischemia-Reperfusion Injury in Liver Transplantation: Stratified Analysis Based on Donor Age
Poster Number: P2.08.147
Date/Time: Monday August 4, 2025, 3:30 PM – 4:30 PM PT
Location: Moscone Center, Exhibit Hall AB
Speaker: Marco Maria Pascale, MD, Policlinico Universitario Fondazione Agostino Gemelli, Rome, Italy
View Abstract
Poster Presentation:
Session Title: Basic Science
Presentation Title: Mitochondrial Injury and Function Comparing Hypothermic and Normothermic Machine Perfusion of Human Livers
Poster Number: P3.03.26
Date/Time: Tuesday August 5, 2025, 3:30 PM – 4:30 PM PT
Location: Moscone Center, Exhibit Hall AB
Presenter: Omer Faruk Karakaya, MD, Department of Inflammation and Immunity, Lerner Research Institute – Cleveland Clinic, Cleveland, OH
View Abstract
Oral Abstract Presentation:
Session Title: Expanding the Donor Pool
Presentation Title: Economic Assessment of Hypothermic Oxygenated Machine Perfusion in Liver Transplantation
Poster Number: OA43.7
Date/Time: Tuesday August 5, 2025, 5:26 PM – 5:35 PM PT
Location: Moscone Center, Room 154
Presenter: David Axelrod, MD, University Hospitals Cleveland Medical Center, OH
View Abstract | View Presentation
Oral Abstract Presentation:
Session Title: Deceased Donor Management
Presentation Title: Decreased Rejection Severity with Hypothermic Oxygenated Perfusion: Sub Analysis from a Pivotal Multicenter Trial of HOPE for Liver Transplantation
Poster Number: OA51.8
Date/Time: Wednesday August 6, 2025, 9:20 AM – 9:29 AM PT
Location: Moscone Center, Room 20
Presenter: David J. Reich, MD, FACS, Drexel University, Philadelphia, PA
Bridge to HOPE Trial
Review the latest information on our US clinical trial of VitaSmart Hypothermic Oxygenated Perfusion System.
