Ischemia-Reperfusion Injury

Comprehensive review of kidney preservation solutions, including historical evolution, formulation mechanisms, and how solutions influence ischemia-reperfusion injury pathways. Strong [...]

This comparative clinical study evaluates the impact of HOPE on ex-situ split liver grafts used in pediatric recipients, benchmarking outcomes against static cold storage split grafts and living [...]

This abstract presents results from a U.S. pivotal multicenter RCT evaluating early allograft dysfunction (EAD) as a primary outcome in liver transplant clinical trials, using data from the [...]

This study assessed the utility of cell-free DNA (cfDNA), including donor-derived (dd-cfDNA) and mitochondrial cfDNA (mt-cfDNA), as objective pre- and post-transplantation biomarkers of graft [...]

This poster from Dora Gómez Pasantes and colleagues at A Coruña University Hospital describes their experience using hypothermic oxygenated perfusion (HOPE) via the VitaSmart with 31 cadaveric [...]

This abstract reports the results from 100 cases of hypothermic oxygenated perfusion (HOPE) in liver transplantation at a Portuguese transplant center (Unidade Local de Saúde de Coimbra, [...]

This study focuses on the potential of Flavin Mononucleotide (FMN) as a biomarker for predicting organ quality and post-transplant outcomes. FMN, released from mitochondrial complex I during [...]

A review of 203 human livers perfused with NMP, including 154 transplants, revealed that despite well-established viability criteria, 11% of transplanted livers still developed non-anastomotic [...]

This study investigates the impact of end-ischemic Hypothermic Oxygenated Machine Perfusion (HOPE) on split-liver transplantation using a porcine model. The research highlights how HOPE helps [...]