HOPE

Machine perfusion is becoming essential in Indian kidney transplantation as reliance on marginal donors (ECD, DCD) grows. This expert consensus, developed with NOTTO, recommends HMP for all DCD [...]

This bi-centric Belgian study evaluated the impact of end-ischemic HOPE (Hypothermic Oxygenated Perfusion) on very old DCD liver grafts (?70 years old). Compared with static cold storage, HOPE [...]

This review provides a modern overview of abdominal organ preservation solutions and how the field is evolving in parallel with machine perfusion. It summarizes key solution compositions, [...]

This comparative clinical study evaluates the impact of HOPE on ex-situ split liver grafts used in pediatric recipients, benchmarking outcomes against static cold storage split grafts and living [...]

This review provides a practical overview of machine perfusion modalities in pediatric liver transplantation and why they may be particularly relevant in children (limited donor pool, small graft [...]

Explore a lecture given by Professor Dutkowski of Switzerland on the treatment and assessment of liver grafts on HOPE. The lecture explores the mechanism of ischemia in organ transplantation and [...]

This study examines the role of Hypothermic Oxygenated Machine Perfusion (HOPE) in mitigating post-reperfusion syndrome (PRS) and perioperative electrolyte shifts during liver transplantation. [...]

Highlights the roles of endothelial cells and mitochondria in liver transplantation, focusing on ischemia-reperfusion injury (IRI). Mitochondrial dysfunction during IRI triggers oxidative stress, [...]

This review article discusses the mechanisms of ischemia-reperfusion injury (IRI) in marginal liver grafts, particularly in the context of Hypothermic Oxygenated Machine Perfusion (HOPE). IRI is [...]