This review provides a practical overview of machine perfusion modalities in pediatric liver transplantation and why they may be particularly relevant in children (limited donor pool, small graft requirements, and frequent use of split grafts). It summarizes early clinical experience with HOPE and related approaches, positioning machine perfusion as a strategy to improve preservation quality, mitigate ischemia-reperfusion injury, and support broader donor acceptance in pediatric practice.
Verma S, Kumar V, Jaiswal P. The Role of Machine Perfusion for Liver Transplantation in Children. J Clin Med. 2025 Jul 19;14(14):4852. doi: 10.3390/jcm14144852. PMID: 41053978.
