This review explores the impact of ischemia-reperfusion injury (IRI) on tumor recurrence following liver transplantation and evaluates the role of machine perfusion (MP) in mitigating these risks. The study focuses on mitochondrial dysfunction as a key factor in post-transplant inflammation and cancer recurrence.
Parente A, Flores Carvalho M, Eden J, Dutkowski P, Schlegel A. Mitochondria and Cancer Recurrence after Liver Transplantation-What Is the Benefit of Machine Perfusion?. Int J Mol Sci. 2022;23(17):9747. Published 2022 Aug 28. doi:10.3390/ijms23179747
