This comparative clinical study evaluates the impact of HOPE on ex-situ split liver grafts used in pediatric recipients, benchmarking outcomes against static cold storage split grafts and living donor liver transplantation. The paper is highly relevant to pediatric programs because it directly addresses the intersection of HOPE with split-graft strategy, and reports outcomes consistent with reduced ischemia-reperfusion injury burden and clinically favorable early graft performance signals.
Rossignol G, Lunsford KE, Chedid MF, et al. HOPE mitigates ischemia-reperfusion injury in ex-situ split grafts: a comparative study with living donation in pediatric liver transplantation. Transpl Int. 2024 Jun 10;37:13029. doi: 10.3389/ti.2024.13029. PMID: 38911062.
