Highlights the roles of endothelial cells and mitochondria in liver transplantation, focusing on ischemia-reperfusion injury (IRI). Mitochondrial dysfunction during IRI triggers oxidative stress, damaging endothelial cells. Hypothermic oxygenated machine perfusion (HOPE) helps protect these cells and reduce complications by preserving mitochondrial function, improving post-transplant outcomes.
Parente A, Flores Carvalho M, Schlegel A. Endothelial Cells and Mitochondria: Two Key Players in Liver Transplantation. Int J Mol Sci. 2023;24(12):10091. Published 2023 Jun 13. doi:10.3390/ijms241210091
